The truth about detox programmes: what science actually says
By Mabonga Makhanu, October 5, 2025You’ve probably come across a detox programme or two in your pursuit of better health.
These programmes are based on the idea that your body is constantly accumulating toxins and needs a “spring cleaning” every now and then.
Usually, such programmes involve a combination of fasting, juicing, eating selected foods, taking supplements, and enemas.
The idea of “spring cleaning” your body sounds appealing, but is it actually backed by science? After all, the human body already has a complete detoxification system, with the liver, kidneys, skin, and intestines working continuously to remove waste and harmful substances.
Scientific research
Most detox programmes have not undergone rigorous scientific studies or clinical trials.
Even the few studies that exist often suffer from small sample sizes, lack of control groups, and over-reliance on self-reporting.
It’s much easier to find scientific studies on individual detox techniques, such as fasting and juicing, than on entire detox programmes.
Juicing
Vegetables are undeniably good for you, but that doesn’t mean it’s wise to give up whole foods entirely and live on juices. Unpasteurised juices, for instance, can contain harmful bacteria that pose serious health risks, especially for people with weakened immune systems.
Additionally, juices made with high-oxalate ingredients, such as spinach or rhubarb, can be hazardous for individuals with kidney problems. Likewise, fruit-heavy juices can raise blood sugar levels, making them risky for diabetics.
Moderation is key when it comes to juicing. You can enjoy the nutritional benefits of fresh vegetable and fruit juices while still eating whole, unprocessed foods to maintain balance.
Fasting
Fasting is probably the most studied detox technique. Research shows it can lower blood sugar levels, reduce inflammation, and offer benefits to those with diabetes or other degenerative conditions.
Short-term fasting can also help restore and replenish tissues; for example, liver tissues regenerate faster during fasting periods.
However, fasting isn’t for everyone. Dry and water fasts can be extremely difficult, causing headaches, weakness, dehydration, and fainting. That’s why most people prefer intermittent fasting, cycling between periods of fasting and eating normally.
Colon cleansing
Supporters of colon cleansing claim that it removes toxins from the colon and alleviates symptoms of allergies, arthritis, and asthma. Unfortunately, there’s no scientific evidence to support these claims.
In fact, studies suggest colon cleansing can cause vomiting, electrolyte imbalance, and even kidney failure.
While juicing and fasting may have limited benefits when practised safely, colon cleansing is one detox method best avoided; the risks far outweigh any potential rewards.
The bottom line
The jury is still out on the effectiveness of detox programmes. It’s best to approach them with caution and always consult your doctor before trying one.
Your body already has an efficient system for handling toxins. Maintaining a healthy diet, drinking enough water, exercising regularly, and getting sufficient sleep are often all you need to stay healthy and energised.
If you’re feeling sluggish or unwell, it’s wise to seek medical advice before starting any cleanse or detox regimen.